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Fast. Lasts. And the Look.*

Discover the DAXXIFY® difference.

The first and only frown line treatment with a peptide formulation.

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*In clinical trial diaries, patients reported seeing a measurable improvement within 2 days of treatment. 74% achieved a ≥ 2-grade improvement at week 4 per both physician's and patient’s assessment. More than 50% had no or minor frown lines until 6 months after treatment per both physician's and patient's assessments. In an open label study (N=27), 96% of patients agreed their skin looked smooth in the glabella (exploratory endpoint).
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The first and only peptide-formulated frown line treatment.

Not all neurotoxin formulations are alike. Our unique peptide formula is the first innovation of its kind in over 20 years.

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The first and only peptide-powered frown line treatment.

See results fast.

DAXXIFY® kicks in quickly. Results are seen as early as the next day and typically within 2 days after treatment.*

See how *In clinical trial diaries, patients reported seeing a measurable improvement within 2 days of treatment.
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Real DAXXIFY® patient. Results may vary.

Watch results last.

DAXXIFY® is long-lasting, keeping your frown lines smooth with a gradual softening over time.†

Explore real results

†74% achieved a ≥ 2-grade improvement at week 4 per both physician's and patient’s assessment. More than 50% had no or minor frown lines until 6 months after treatment per both physician's and patient's assessments.

Get the radiant look.

DAXXIFY® smooths even the deepest lines and gets results that look radiant.‡

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‡In a separate survey (N=27), 89% of patients rated their skin as radiant/bright.

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Real DAXXIFY® patient. Results may vary.

Awards worth talking about.

Elle Tools and Treatments Award 2024

Elle Tools and Treatments Award 2024

Aesthetic Treatment Award Winner

Cosmo Holy Grail Beauty Award 2024

Cosmo Holy Grail Beauty Award 2024

Best Game-Changing Pro Treatment

Shape Skin Award 2024

Shape Skin Award 2024

Best Injectable for Long-Lasting Results

Elle Tools and Treatments Award 2024

Elle Tools and Treatments Award 2024

Best Glow-Boosting Neurotoxin

Time Best Inventions 2023

Time Best Inventions 2023

Smoother skin

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IMPORTANT SAFETY INFORMATION for DAXXIFY® (daxibotulinumtoxinA-Ianm) injection
DAXXIFY® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of DAXXIFY®: • Problems swallowing, speaking, or breathing due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection.

IMPORTANT SAFETY INFORMATION for DAXXIFY® (daxibotulinumtoxinA-Ianm) injection

DAXXIFY® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of DAXXIFY®:

• Problems swallowing, speaking, or breathing due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.

• Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms that include loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.

Do not receive DAXXIFY® if you are allergic to any of the ingredients in DAXXIFY® (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®/BOTOX® Cosmetic), abobotulinumtoxinA (DYSPORT®), incobotulinumtoxinA (XEOMIN®) or prabotulinumtoxinA-xvfs (JEUVEAU®), or have a skin infection at the planned injection site.

DAXXIFY® dosing units are not the same as, or comparable to, any other botulinum toxin product.

Tell your healthcare provider about all your medical conditions, including any side effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles; drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using DAXXIFY® with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your healthcare provider that you have received DAXXIFY® in the past.

Especially tell your healthcare provider if you have received any other botulinum toxin product in the last 4 months or any in the past, and exactly which product you received (such as BOTOX®, BOTOX® Cosmetic, MYOBLOC®, DYSPORT®, XEOMIN®, or JEUVEAU®). DAXXIFY® may cause serious side effects, including allergic reactions (such as itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint), heart problems (such as irregular heartbeat and heart attack), and eye problems (including dry eye, reduced blinking, and corneal problems). Tell your healthcare provider or get medical help right away if you experience a serious side effect. No serious adverse events of distant spread of toxin effect associated with dermatologic use of DAXXIFY® have been reported in clinical studies at the dose of 40 Units for glabellar lines. The most common side effects of DAXXIFY® include headache, eyelid drooping, and loss of ability to move the muscles in your face.

These are not all the possible side effects of DAXXIFY®. For more information, see the full Prescribing Information including Boxed Warning, and refer to the Medication Guide or talk with your doctor. To report side effects associated with DAXXIFY®, please call 1-877-373-8669. You may also report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

APPROVED USE
DAXXIFY® is a prescription medicine that is injected into muscles and used in adults to temporarily improve the look of moderate to severe frown lines between the eyebrows.

DAXI-001723.2

©2025 REVANCE.
DAXXIFY, REVANCE THERAPEUTICS AND THE REVANCE LOGO ARE REGISTERED TRADEMARKS OF REVANCE THERAPEUTICS, INC. RHA® AND RHA REDENSITY® ARE REGISTERED TRADEMARKS OF TEOXANE SA, MANUFACTURED IN SWITZERLAND. THE TEOXANE RHA® COLLECTION IS EXCLUSIVELY DISTRIBUTED BY REVANCE®. ALL OTHER TRADEMARKS ARE THE PROPERTY OF THEIR RESPECTIVE OWNERS.

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